Newsgroup sci.techniques.mass-spec 1152

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Im trying to set up an LC-MS method for the analysis of a rat poison 
(brodifacoum) but have found that in ESI the chromatogram is inverted ie 
the analyte apparently suppresses the background ion current.  The 
effect is the same in positive and negative mode, and I havent tried 
APCI yet to see if the effect is the same.  Is there a way around this 
to get my chromatograms the right way up?!

In article <58jpa6$boh@acmey.gatech.edu> jjmorelli@aol.com  writes:
} One added advantage of Turbo pumps irrespective of their pumping speed and
} performance is that air cooled models are available.  Often water cooling
} can be difficult or impossible. Anyone who has had to repair a water leak
} from an aging water cooled system can attest to this problem.  There is
} also the issue of the quality of water supplied.  In a closed system,
} chillers are required.  These can develop salting problems and be an
} additional maitanence item.
} 
} Warning!! The above is a very biased, unobjective opinion. I love TURBOS! 
It is worth pointing out that if you are in an area prone to sharp 
earthquakes that ceramic bearings are a good choice, and unless 
things have improved a lot mag-lev bearings can be disastrous.
Regards,
-- 
Martin Brown       __                CIS: 71651,470
Scientific Software Consultancy             /^,,)__/

Hello,
	I am interested in purchasing an octopole ion guide.  I have
had some difficulty in locating a company that manufactures them and
would greatly appreciate any assistance.
Thank You,
Rich Bell
Penn State University
email:  rich@opus.chem.psu.edu